top of page
This site was designed with the
.com
website builder. Create your website today.Start Now

PUBLICATIONS

 

​

​

​

​

​

​

  • Effects of defective unloading and recycling of PCNA revealed by the analysis of ELG1 mutants. Itzkovich Z., Choudhary K., Arbel M., and M. Kupiec (2023) Int J Mol Sci. 2023 Jan 13;24(2):1568. doi: 10.3390/ijms24021568. PMID: 36675081.

​

  • The polyHIS Tract of Yeast AMPK Coordinates Carbon Metabolism with Iron Availability. Simpson-Lavy, K and M. Kupiec (2023) Intl. Journal of Molecular Sciences 24:1368. https://doi.org/10.3390/ijms24021368

​

  • A comparative analysis of telomere length maintenance circuits in fission and budding yeast.  Peretz, I., Kupiec M.* and R. Sharan* (2022) Frontiers in Genetics 13:1033113. doi: 10.3389/fgene.2022.1033113.

​

  • The cohesin complex of yeasts: sister chromatid cohesion and beyond. Choudhary, K., and M. Kupiec (2022) FEMS Microbiology Reviews fuac045. doi: 10.1093/femsre/fuac045. PMID: 36370456.

​

  • S. cerevisiae cells can grow without the Pds5 cohesin subunit. Choudhary, K., Itzkovich, Z., Alonso-Perez, E., Bishara, H., Dunn, B., Sherlock, G.and M. Kupiec (2022) mBio 13(4):e0142022. doi: 10.1128/mbio.01420-22. PMID: 35708277.

​

  • Regulation of yeast AMPK by a poly-histidine containing pH sensing module.Simpson-Lavy, K and M. Kupiec (2022) iScience. 25(10):105083. doi: 10.1016/j.isci.2022.105083.

​

  • TOR complex 2 contributes to regulation of gene expression via inhibition of Gcn5 recruitment to subtelomeric and DNA replication stress genes. Cohen, A., Pataki, E., Kupiec, M. and R. Weisman (2022) PLoS Genet. 2022 Feb 14;18(2):e1010061. doi: 10.1371/journal.pgen.1010061

​

  • Metabolic remodeling maintains a reducing environment for rapid activation of the yeast DNA replication checkpoint.  Li, L., Wang, J., Yang, Z., Zhao, Y., Jiang, H., Jiang, L., Hou, W., Ye, R., He, Q., Kupiec, M.,  Luke, B., Cao, Q., Qi, Z., Li, Z., and H. Lou (2022) EMBO J. e108290. doi: 10.15252/embj.2021108290.

​​

  • PCNA loaders and unloaders – one ring that rules them all. Arbel, M., Choudhary, K., Tfilin, O., and M. Kupiec (2021) Genes (Basel) 12:1812. doi: 10.3390/genes12111812.

​

  • Split chloramphenicol acetyl-transferase assay reveals self-ubiquitylation-dependent regulation of UBE3B. Levin-Kravets O, Kordonsky A, Shusterman A, Biswas S, Persaud A, Elias S, Langut Y, Florentin A, Simpson-Lavy KJ, Yariv E, Avishid R, Sror M, Almog O, Marshanski T, Kadosh S, Ben David N, Manori B, Fischer Z, Lilly J, Borisova E, Ambrozkiewicz MC, Tarabykin V, Kupiec M, Thaker M, Rotin D, Prag G (2021) J. Mol. Biol. 29:167276. doi: 10.1016/j.jmb.2021.167276. PMID: 34599943

​​

  • The Amazing Acrobat: Yeast's Histone H3K56 Juggles Several Important Roles While Maintaining Perfect Balance.Gershon, L. and M. Kupiec (2021) Genes (Basel). 12:342. doi: 10.3390/genes12030342.

​

  • Histones on fire: the effect of Dun1 and Mrc1 on origin firing and replication of hyper-acetylated genomes. Gershon, L. and M. Kupiec (2021) Current Genetics 67:501-510. doi: 10.1007/s00294-021-01175-2.

​​

  • A novel role for Dun1 in the regulation of origin firing upon hyper-acetylation of H3K56. Gershon, L. and M. Kupiec (2021) PLoS Genetics,  17::e1009391. doi: 10.1371/journal.pgen.1009391..

​

  • Noise buffering by biomolecular condensates in glucose sensing. Simpson-Lavy K. amd M. Kupiec (2021) Curr Opin Cell Biol. 2020 Dec 31;69:1-6. doi: 10.1016/j.ceb.2020.12.002.

​

  • DNA damage bypass pathways and their effect on mutagenesis in yeast. Arbel, M., Liefshitz, B. and M. Kupiec (2021) FEMS Microbiological Reviews fuaa038. doi: 10.1093/femsre/fuaa038.

​

  • Editorial. Kupiec M. and M. Polymenis (2020) Curr Genet. doi: 10.1007/s00294-020-01131-6.

​

  •  TOR Complex 2- independent mutations in the regulatory PIF pocket of Gad8AKT1/SGK1 define separate branches of the stress response mechanisms in fission yeast. Pataki, E., Cohen, A., Simhaev, L., Engel, H., Kupiec, M. and Ronit Weisman (2020). PLoS Genetics 16(11):e1009196. doi: 10.1371.

​

  • The Third International Symposium on Fungal Stress - ISFUS.Alder-Rangel, A., Idnurm, A., Brand, A.C., Brown, A.J.P., Gorbushina, A., Kelliher, C.M., Campos, C.B., Levin, D.E., Bell-Pedersen, D., Dadachova, E., Bauer, F.F., Gadd, G.M., Braus, G.H., Braga, G.U.L., Brancini, G.T.P., Walker, G.M., Druzhinina, I., Pócsi, I., Dijksterhuis, J., Aguirre, J., Hallsworth, J.E., Schumacher, J., Wong, K.H., Selbmann, L., Corrochano, L.M., Kupiec, M., Momany, M., Molin, M., Requena, N., Yarden, O., Cordero, R.J.B., Fischer, R., Pascon, R.C., Mancinelli, R.L., Emri, T., Basso, T.O., Rangel, D.E.N. (2020) Fungal Biol. 124:235-252.

​​

  • G2G: A web-server for the prediction of human synthetic lethal interactions. Almozlino YT, Peretz I, Kupiec M, Sharan R. Comput Struct Biotechnol J. 2020;18:1028‐1031. Published 2020 Apr 27. doi:10.1016/j.csbj.2020.04.012

​​

  • How yeast cells deal with stalled replication forks. Arbel M, Liefshitz B, Kupiec M. Curr Genet. 2020;10.1007/s00294-020-01082-y. doi:10.1007/s00294-020-01082-y

​​

  • Telomeres and stress in yeast cells: When genes and environment interact. Harari Y, Gershon L, Alonso-Perez E, Klein S, Berneman Y, Choudhari K, Singh P, Sau S, Liefshitz B, Kupiec M. Fungal Biol. 2020;124(5):311‐315. doi:10.1016/j.funbio.2019.09.003

​

  • Access to PCNA by Srs2 and Elg1 Controls the Choice between Alternative Repair Pathways in Saccharomyces cerevisiae Arbel M, Bronstein A, Sau S, Liefshitz B, Kupiec M. mBio. 2020;11(3):e00705-20. Published 2020 May 5. doi:10.1128/mBio.00705-20

 

  • The cytosolic form of aspartate aminotransferase is required for full activation of TOR complex 1 in fission yeast. Reidman S, Cohen A, Kupiec M, Weisman R. J Biol Chem. 2019;294(48):18244‐18255. doi:10.1074/jbc.RA119.010101

 

  • Genome architecture and stability in the Saccharomyces cerevisiae knockout collection. Puddu F, Herzog M, Selivanova A, Wang S, Zhu J, Klein-Lavi S, Gordon M, Meirman R, Millan-Zambrano G, Ayestaran I, Salguero I, Sharan R, Li R, Kupiec M, Jackson SP. Nature. 2019;573(7774):416‐420. doi:10.1038/s41586-019-1549-9

​

  • A role for the yeast PCNA unloader Elg1 in eliciting the DNA damage checkpoint. Sau S, Kupiec M. Curr Genet. 2020;66(1):79‐84. doi:10.1007/s00294-019-01020-7

​

  • The Yeast PCNA Unloader Elg1 RFC-Like Complex Plays a Role in Eliciting the DNA Damage Checkpoint. Sau S, Liefshitz B, Kupiec M. mBio. 2019;10(3):e01159-19. Published 2019 Jun 11. doi:10.1128/mBio.01159-19

 

  • Carbon catabolite repression: not only for glucose. Simpson-Lavy K, Kupiec M. Curr Genet. 2019;65(6):1321‐1323. doi:10.1007/s00294-019-00996-6

 

  • Carbon Catabolite Repression in Yeast is Not Limited to Glucose. Simpson-Lavy K, Kupiec M. Sci Rep. 2019;9(1):6491. Published 2019 Apr 24. doi:10.1038/s41598-019-43032-w

​

  • Comparative Analysis of Normalization Methods for Network Propagation. Biran H, Kupiec M, Sharan R. Front Genet. 2019;10:4. Published 2019 Jan 22. doi:10.3389/fgene.2019.00004

​

  • The Main Role of Srs2 in DNA Repair Depends on Its Helicase Activity, Rather than on Its Interactions with PCNA or Rad51. Bronstein A, Gershon L, Grinberg G, Alonso-Perez E, Kupiec M. mBio. 2018;9(4):e01192-18. Published 2018 Jul 17. doi:10.1128/mBio.01192-18

​

  • TOR complex 2 in fission yeast is required for chromatin-mediated gene silencing and assembly of heterochromatic domains at subtelomeres. Cohen A, Habib A, Laor D, Yadav S, Kupiec M, Weisman R J Biol Chem. 2018;293(21):8138‐8150. doi:10.1074/jbc.RA118.002270

​​

  • TOR complex 2 in fission yeast is required for chromatin-mediated gene silencing and assembly of heterochromatic domains at subtelomeres.    Cohen A, Habib A, Laor D, Yadav S, Kupiec M, Weisman R J Biol Chem. 2018;293(21):8138‐8150. doi:10.1074/jbc.RA118.002270

​​

  • Tight Regulation of Srs2 Helicase Activity Is Crucial for Proper Functioning of DNA Repair Mechanisms. Bronstein A, Bramson S, Shemesh K, Liefshitz B, Kupiec M. G3 (Bethesda). 2018 May 4;8(5):1615-1626. doi: 10.1534/g3.118.200181.
     

  • The Main Role of Srs2 in DNA Repair Depends on Its Helicase Activity, Rather than on Its Interactions with PCNA or Rad51. Bronstein A, Gershon L, Grinberg G, Alonso-Perez E, Kupiec M. MBio. 2018 Jul 17;9(4). pii: e01192-18. doi: 10.1128/mBio.01192-18.
     

  • TOR complex 2 is required for chromatin-mediated gene silencing and assembly of heterochromatic domains at subtelomeres. Cohen, A., Habib, A., Laor, D., Yadav, S., Kupiec, M and R.  Weisman . 2018. JBC, in press.

​​

  • Frequent ploidy changes in growing yeast cultures.  Harari Y, Ram Y, and M. Kupiec . 2018. Curr Genet. 2018 Mar 10. doi: 10.1007/s00294-018-0823-y.PMID: 29525927

​​

  • WebPropagate : a web-server for network propagation.  Biran, H., Almozlino, T., Kupiec, M. and R. Sharan . 2018. J Mol Biol. 2018 Mar 7. pii: S0022-2836(18)30112-8. doi: 10.1016/j.jmb.2018.02.025. PMID: 29524510.

​​

  • Slight overexpression of the Srs2 helicase uncovers DNA damage response mechanisms in yeast.  Bronstein, A., Bramson, S., Shemesh,K., Liefshitz, Batia and M. Kupiec (2018) Genes, Genomics, Genetics (3G) pii: g3.200181.2018. doi: 10.1534/g3.118.200181.

​​

  • Pivotal roles of PCNA loading and unloading on heterochromatin function. Janke, R., King, G., Kupiec, M. and J. Rine (2018) Proc. Natl. Acad. Sci. USA, doi: 10.1073/pnas.1721573115.

​​

  • A reversible liquid crystal aggregation controls glucose response in yeast. Simpson-Lavy, K. and M. Kupiec . 2018).Current Genetics doi: 10.1007/s00294-018-08050.

​​

  • The extent of ribosome queuing in budding yeast.  Diament, A., Feldman, A., Schochet. E., Kupiec, M., Arava, Y., and T. Tuller. 2018. PLoS Comput Biol. 2018 Jan 29;14(1):e1005951. doi: 10.1371/journal.pcbi.1005951.

​​

  • Spontaneous changes in ploidy are common in yeast.  Harari, Y., Ram, Y., Rappoport, N., Hadany, L. and M. Kupiec. 2018. Curr. Biology, 2018 Mar 19;28(6):825-835.e4. doi: 10.1016/j.cub.2018.01.062. PMID: 29502947

​​

  • The Std1 activator of the Snf1/AMPK kinase controls glucose response in yeast by a regulated protein aggregation. Simpson-Lavy, K., Xu, T., Johnston, M., Kupiec M. 2017. Molecular Cell 68:1120-1133. Commented by: A droplet to sense sugar drops. Barral, Y., Caudron, F.  Mol Cell 68: 101701019.

​​

  • Rnr1's role in telomere elongation cannot be replaced by Rnr3: a role beyond dNTPs? Maicher A, Kupiec M.. Curr Genet. 2017 Nov 8. doi: 10.1007/s00294-017-0779-3.

​​

  • The evolutionarily conserved factor Sus1/ENY2 plays a role in telomere length maintenance. Galán A, García-Oliver E, Nuño-Cabanes C, Rubinstein L, Kupiec M, Rodríguez-Navarro S. Curr Genet. 2017 Nov 7. doi: 10.1007/s00294-017-0778-4. 

​​

  • Rnr1, but not Rnr3, facilitates the sustained telomerase-dependent elongation of telomeres. Maicher A, Gazy I, Sharma S, Marjavaara L, Grinberg G, Shemesh K, Chabes A, Kupiec M. PLoS Genet. 2017 Oct 25;13(10):e1007082. doi: 10.1371/journal.pgen.1007082. PMID:28851852 | PMCID:PMC5574717
     

  • Do long telomeres affect cellular fitness? Harari Y, Kupiec M. Curr Genet. 2017 Sep 8. doi: 10.1007/s00294-017-0746-z. Review. PMID:28780613
     

  • Long Telomeres Do Not Affect Cellular Fitness in Yeast. Harari Y, Zadok-Laviel S, Kupiec M. MBio. 2017 Aug 29;8(4). pii: e01314-17. doi: 10.1128/mBio.01314-17. PMID:28549478 | PMCID:PMC5446740
     

  • Mec1(ATR) is needed for extensive telomere elongation in response to ethanol in yeast. Harari Y, Kupiec M. Curr Genet. 2017 Aug 5. doi: 10.1007/s00294-017-0728-1. [Epub ahead of print] PMID:28476868 | PMCID:PMC5500160
     

  • GLADIATOR: a global approach for elucidating disease modules. Silberberg Y, Kupiec M, Sharan R. Genome Med. 2017 May 26;9(1):48. doi: 10.1186/s13073-017-0435-z. PMID:28108661 | PMCID:PMC5389545
     

  • A New Method, "Reverse Yeast Two-Hybrid Array" (RYTHA), Identifies Mutants that Dissociate the Physical Interaction Between Elg1 and Slx5. Lev I, Shemesh K, Volpe M, Sau S, Levinton N, Molco M, Singh S, Liefshitz B, Ben Aroya S, Kupiec M. Genetics. 2017 Jul;206(3):1683-1697. doi: 10.1534/genetics.117.200451. Epub 2017 May 5. PMID:28069708 | PMCID:PMC5437815
     

  • A structure-function analysis of the yeast Elg1 protein reveals the importance of PCNA unloading in genome stability maintenance. Shemesh K, Sebesta M, Pacesa M, Sau S, Bronstein A, Parnas O, Liefshitz B, Venclovas C, Krejci L, Kupiec M. Nucleic Acids Res. 2017 Apr 7;45(6):3189-3203. doi: 10.1093/nar/gkw1348. PMID:27834202 | PMCID:PMC5101353
     

  • Ubiquitylation-dependent oligomerization regulates activity of Nedd4 ligases. Attali I, Tobelaim WS, Persaud A, Motamedchaboki K, Simpson-Lavy KJ, Mashahreh B, Levin-Kravets O, Keren-Kaplan T, Pilzer I, Kupiec M, Wiener R, Wolf DA, Rotin D, Prag G. EMBO J. 2017 Feb 15;36(4):425-440. doi: 10.15252/embj.201694314. Epub 2017 Jan 9. PMID:27664980
     

  • Role of the ESCRT Complexes in Telomere Biology. Dieckmann AK, Babin V, Harari Y, Eils R, Kֳ¶nig R, Luke B, Kupiec M. MBio. 2016 Nov 8;7(6). pii: e01793-16. doi: 10.1128/mBio.01793-16. PMID:27025271 | PMCID:PMC4812343
     

  • Alternative clamp loaders/unloaders. Kupiec M. FEMS Yeast Res. 2016 Nov;16(7). pii: fow084. Epub 2016 Sep 24. Review. PMID:26912660 | PMCID:PMC4861499
     

  • Utilizing yeast chemogenomic profiles for the prediction of pharmacogenomic associations in humans. Silberberg Y, Kupiec M, Sharan R. Sci Rep. 2016 Mar 30;6:23703. doi: 10.1038/srep23703. PMID:26908654 | PMCID:PMC4889924
     

  • Gad8 Protein Is Found in the Nucleus Where It Interacts with the MluI Cell Cycle Box-binding Factor (MBF) Transcriptional Complex to Regulate the Response to DNA Replication Stress. Cohen A, Kupiec M, Weisman R. J Biol Chem. 2016 Apr 22;291(17):9371-81. doi: 10.1074/jbc.M115.705251. Epub 2016 Feb 24. PMID:26602688 | PMCID:PMC4797274
     

  • Mixed Integer Linear Programming based machine learning approach identifies regulators of telomerase in yeast. Poos AM, Maicher A, Dieckmann AK, Oswald M, Eils R, Kupiec M, Luke B, Kֳnig R. Nucleic Acids Res. 2016 Jun 2;44(10):e93. doi: 10.1093/nar/gkw111. Epub 2016 Feb 22. PMID:26344768 | PMCID:PMC4581987
     

  • Systematic identification and correction of annotation errors in the genetic interaction map of Saccharomyces cerevisiae. Atias N, Kupiec M, Sharan R. Nucleic Acids Res. 2016 Mar 18;44(5):e50. doi: 10.1093/nar/gkv1284. Epub 2015 Nov 23. PMID:26177013 | PMCID:PMC4825795
     

  • Cross-Talk between Carbon Metabolism and the DNA Damage Response in S. cerevisiae. Simpson-Lavy KJ, Bronstein A, Kupiec M, Johnston M. Cell Rep. 2015 Sep 22;12(11):1865-75. doi: 10.1016/j.celrep.2015.08.025. Epub 2015 Sep 3. PMID:26152587 | PMCID:PMC4488950
     

  • Regulation of Elg1 activity by phosphorylation. Shkedy D, Singh N, Shemesh K, Amir A, Geiger T, Liefshitz B, Harari Y, Kupiec M. Cell Cycle. 2015;14(23):3689-97. doi: 10.1080/15384101.2015.1068475. PMID:26116075
     

  • TORC1 Regulates Developmental Responses to Nitrogen Stress via Regulation of the GATA Transcription Factor Gaf1. Laor D, Cohen A, Kupiec M, Weisman R. MBio. 2015 Jul 7;6(4):e00959. doi: 10.1128/mBio.00959-15. PMID:25895946
     

  • Fungal stress biology: a preface to the Fungal Stress Responses special edition. Rangel DE, Alder-Rangel A, Dadachova E, Finlay RD, Kupiec M, Dijksterhuis J, Braga GU, Corrochano LM, Hallsworth JE. Curr Genet. 2015 Aug;61(3):231-8. doi: 10.1007/s00294-015-0500-3. Epub 2015 Jun 27. PMID:25827723

​​

  • Elg1, a central player in genome stability. Gazy I, Liefshitz B, Parnas O, Kupiec M. Mutat Res Rev Mutat Res. 2015 Jan-Mar;763:267-79. doi: 10.1016/j.mrrev.2014.11.007. Epub 2014 Nov 24. Review. PMID:25451739
     

  • The effects of telomere shortening on cancer cells: a network model of proteomic and microRNA analysis. Uziel O, Yosef N, Sharan R, Ruppin E, Kupiec M, Kushnir M, Beery E, Cohen-Diker T, Nordenberg J, Lahav M. Genomics. 2015 Jan;105(1):5-16. doi: 10.1016/j.ygeno.2014.10.013. Epub 2014 Nov 13. PMID:24928510 | PMCID:PMC4118131
     

  • Glycan degradation (GlyDeR) analysis predicts mammalian gut microbiota abundance and host diet-specific adaptations. Eilam O, Zarecki R, Oberhardt M, Ursell LK, Kupiec M, Knight R, Gophna U, Ruppin E. MBio. 2014 Aug 12;5(4). pii: e01526-14. doi: 10.1128/mBio.01526-14. PMID:24754043
     

  • Glucose activates TORC2-Gad8 protein via positive regulation of the cAMP/cAMP-dependent protein kinase A (PKA) pathway and negative regulation of the Pmk1 protein-mitogen-activated protein kinase pathway. Cohen A, Kupiec M, Weisman R. J Biol Chem. 2014 Aug 1;289(31):21727-37. doi: 10.1074/jbc.M114.573824. Epub 2014 Jun 13. PMID:24728996 | PMCID:PMC4041441
     

  • Biology of telomeres: lessons from budding yeast. Kupiec M. FEMS Microbiol Rev. 2014 Mar;38(2):144-71. Review. PMID:24682826 | PMCID:PMC4027216
     

  • Telomere length kinetics assay (TELKA) sorts the telomere length maintenance (tlm) mutants into functional groups. Rubinstein L, Ungar L, Harari Y, Babin V, Ben-Aroya S, Merenyi G, Marjavaara L, Chabes A, Kupiec M. Nucleic Acids Res. 2014 Jun;42(10):6314-25. doi: 10.1093/nar/gku267. Epub 2014 Apr 11. PMID:24625764 | PMCID:PMC3953217
     

  • A high-throughput chemical screen with FDA approved drugs reveals that the antihypertensive drug Spironolactone impairs cancer cell survival by inhibiting homology directed repair. Shahar OD, Kalousi A, Eini L, Fisher B, Weiss A, Darr J, Mazina O, Bramson S, Kupiec M, Eden A, Meshorer E, Mazin AV, Brino L, Goldberg M, Soutoglou E. Nucleic Acids Res. 2014 May;42(9):5689-701. doi: 10.1093/nar/gku217. Epub 2014 Mar 25. PMID:28357225 | PMCID:PMC5349225
     

  • A method for predicting protein-protein interaction types. Silberberg Y, Kupiec M, Sharan R. PLoS One. 2014 Mar 13;9(3):e90904. doi: 10.1371/journal.pone.0090904. eCollection 2014. PMID:24344203 | PMCID:PMC4023818
     

  • Genome-wide studies of telomere biology in budding yeast. Harari Y, Kupiec M. Microb Cell. 2014 Mar 1;1(3):70-80. doi: 10.15698/mic2014.01.132. Review. PMID:24262150 | PMCID:PMC3856780
     

  • Isp7 is a novel regulator of amino acid uptake in the TOR signaling pathway. Laor D, Cohen A, Pasmanik-Chor M, Oron-Karni V, Kupiec M, Weisman R. Mol Cell Biol. 2014 Mar;34(5):794-806. doi: 10.1128/MCB.01473-13. Epub 2013 Dec 16. Erratum in: Mol Cell Biol. 2014 Apr;34(8):1535.  PMID:24091626 | PMCID:PMC3906331
     

  • Genomic instability and repair mediated by common repeated sequences. Gazy I, Kupiec M. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19664-5. doi: 10.1073/pnas.1320030110. Epub 2013 Nov 21. No abstract available.  PMID:24039592 | PMCID:PMC3764183
     

  • Nature vs nurture: interplay between the genetic control of telomere length and environmental factors. Harari Y, Romano GH, Ungar L, Kupiec M. Cell Cycle. 2013 Nov 15;12(22):3465-70. doi: 10.4161/cc.26625. Epub 2013 Sep 26. PMID:23704284 | PMCID:PMC3656737
     

  • Environmental stresses disrupt telomere length homeostasis. Romano GH, Harari Y, Yehuda T, Podhorzer A, Rubinstein L, Shamir R, Gottlieb A, Silberberg Y, Pe'er D, Ruppin E, Sharan R, Kupiec M. PLoS Genet. 2013;9(9):e1003721. doi: 10.1371/journal.pgen.1003721. Epub 2013 Sep 5. PMID:23703609 | PMCID:PMC3707671
     

  • A genetic screen for high copy number suppressors of the synthetic lethality between elg1 and srs2 in yeast. Gazy I, Liefshitz B, Bronstein A, Parnas O, Atias N, Sharan R, Kupiec M. G3 (Bethesda). 2013 May 20;3(5):917-26. doi: 10.1534/g3.113.005561. PMID:23644470
     

  • TORC2 is required to maintain genome stability during S phase in fission yeast. Schonbrun M, Kolesnikov M, Kupiec M, Weisman R. J Biol Chem. 2013 Jul 5;288(27):19649-60. doi: 10.1074/jbc.M113.464974. Epub 2013 May 23. PMID:23624835 | PMCID:PMC3680542
     

  • Effect of nuclear architecture on the efficiency of double-strand break repair. Agmon N, Liefshitz B, Zimmer C, Fabre E, Kupiec M. Nat Cell Biol. 2013 Jun;15(6):694-9. doi: 10.1038/ncb2745. Epub 2013 May 5. PMID:23197825 | PMCID:PMC3529009
     

  • Genetic and physical interactions between the yeast ELG1 gene and orthologs of the Fanconi anemia pathway. Singh S, Shemesh K, Liefshitz B, Kupiec M. Cell Cycle. 2013 May 15;12(10):1625-36. doi: 10.4161/cc.24756. Epub 2013 Apr 25. PMID:22885325 | PMCID:PMC3443319
     

  • Chromosomal duplication is a transient evolutionary solution to stress. Yona AH, Manor YS, Herbst RH, Romano GH, Mitchell A, Kupiec M, Pilpel Y, Dahan O. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):21010-5. doi: 10.1073/pnas.1211150109. Epub 2012 Nov 29. PMID:22732495
     

  • The Rad1-Rad10 nuclease promotes chromosome translocations between dispersed repeats. Mazֳn G, Lam AF, Ho CK, Kupiec M, Symington LS. Nat Struct Mol Biol. 2012 Sep;19(9):964-71. doi: 10.1038/nsmb.2359. Epub 2012 Aug 12. PMID:22617386
     

  • The importance of being modified: PCNA modification and DNA damage response. Gazy I, Kupiec M. Cell Cycle. 2012 Jul 15;11(14):2620-3. doi: 10.4161/cc.20626. Epub 2012 Jul 15. PMID:22575960
     

  • TOR links starvation responses to telomere length maintenance. Kupiec M, Weisman R. Cell Cycle. 2012 Jun 15;11(12):2268-71. doi: 10.4161/cc.20401. Epub 2012 Jun 15. Review. PMID:22306811
     

  • Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq. Dominissini D, Moshitch-Moshkovitz S, Schwartz S, Salmon-Divon M, Ungar L, Osenberg S, Cesarkas K, Jacob-Hirsch J, Amariglio N, Kupiec M, Sorek R, Rechavi G. Nature. 2012 Apr 29;485(7397):201-6. doi: 10.1038/nature11112. PMID:22300318 | PMCID:PMC3272249
     

  • Systematic identification of gene annotation errors in the widely used yeast mutation collections. Ben-Shitrit T, Yosef N, Shemesh K, Sharan R, Ruppin E, Kupiec M. Nat Methods. 2012 Feb 5;9(4):373-8. doi: 10.1038/nmeth.1890. PMID:22194704 | PMCID:PMC3240591
     

  • Large-scale elucidation of drug response pathways in humans. Silberberg Y, Gottlieb A, Kupiec M, Ruppin E, Sharan R. J Comput Biol. 2012 Feb;19(2):163-74. doi: 10.1089/cmb.2011.0264. PMID:22169538
     

  • An anti-checkpoint activity for rif1. Harari Y, Rubinstein L, Kupiec M. PLoS Genet. 2011 Dec;7(12):e1002421. doi: 10.1371/journal.pgen.1002421. Epub 2011 Dec 15. No abstract available.  PMID:22158444
     

  • Tor complex 1 controls telomere length by affecting the level of Ku. Ungar L, Harari Y, Toren A, Kupiec M. Curr Biol. 2011 Dec 20;21(24):2115-20. doi: 10.1016/j.cub.2011.11.024. Epub 2011 Dec 8. PMID:22054298 | PMCID:PMC3229294
     

  • Competitive and cooperative metabolic interactions in bacterial communities. Freilich S, Zarecki R, Eilam O, Segal ES, Henry CS, Kupiec M, Gophna U, Sharan R, Ruppin E. Nat Commun. 2011 Dec 13;2:589. doi: 10.1038/ncomms1597. PMID:22050731 | PMCID:PMC3334596
     

  • Home and away- the evolutionary dynamics of homing endonucleases. Barzel A, Obolski U, Gogarten JP, Kupiec M, Hadany L. BMC Evol Biol. 2011 Nov 4;11:324. doi: 10.1186/1471-2148-11-324. Identifiers
     

  • Composite effects of gene determinants on the translation speed and density of ribosomes. Tuller T, Veksler-Lublinsky I, Gazit N, Kupiec M, Ruppin E, Ziv-Ukelson M. Genome Biol. 2011 Nov 3;12(11):R110. doi: 10.1186/gb-2011-12-11-r110. PMID:21909250 | PMCID:PMC3164701
     

  • Genome-scale analysis of translation elongation with a ribosome flow model. Reuveni S, Meilijson I, Kupiec M, Ruppin E, Tuller T. PLoS Comput Biol. 2011 Sep;7(9):e1002127. doi: 10.1371/journal.pcbi.1002127. Epub 2011 Sep 1. PMID:21844225 | PMCID:PMC3187367
     

  • Elg1, the major subunit of an alternative RFC complex, interacts with SUMO-processing proteins. Parnas O, Amishay R, Liefshitz B, Zipin-Roitman A, Kupiec M. Cell Cycle. 2011 Sep 1;10(17):2894-903. Epub 2011 Sep 1. PMID:21609961 | PMCID:PMC3167605
     

  • Roles of RSC, Rad59, and cohesin in double-strand break repair. Liefshitz B, Kupiec M. Mol Cell Biol. 2011 Oct;31(19):3921-3. doi: 10.1128/MCB.05974-11. Epub 2011 Aug 15. No abstract available.  PMID:21527600
     

  • The role of Holliday junction resolvases in the repair of spontaneous and induced DNA damage. Agmon N, Yovel M, Harari Y, Liefshitz B, Kupiec M. Nucleic Acids Res. 2011 Sep 1;39(16):7009-19. doi: 10.1093/nar/gkr277. Epub 2011 May 23. PMID:21525128 | PMCID:PMC3159444

​​

  • Native homing endonucleases can target conserved genes in humans and in animal models. Barzel A, Privman E, Peeri M, Naor A, Shachar E, Burstein D, Lazary R, Gophna U, Pupko T, Kupiec M. Nucleic Acids Res. 2011 Aug;39(15):6646-59. doi: 10.1093/nar/gkr242. Epub 2011 Apr 27. PMID:21343180 | PMCID:PMC3113575
     

  • Analysis of coevolving gene families using mutually exclusive orthologous modules. Zhang X, Kupiec M, Gophna U, Tuller T. Genome Biol Evol. 2011;3:413-23. doi: 10.1093/gbe/evr030. Epub 2011 Apr 17. PMID:21265767
     

  • Association between translation efficiency and horizontal gene transfer within microbial communities. Tuller T, Girshovich Y, Sella Y, Kreimer A, Freilich S, Kupiec M, Gophna U, Ruppin E. Nucleic Acids Res. 2011 Jun;39(11):4743-55. doi: 10.1093/nar/gkr054. Epub 2011 Feb 22. PMID:21260952
     

  • Homing endonucleases residing within inteins: evolutionary puzzles awaiting genetic solutions. Barzel A, Naor A, Privman E, Kupiec M, Gophna U. Biochem Soc Trans. 2011 Jan;39(1):169-73. doi: 10.1042/BST0390169. Review. PMID:20874411
     

  • Establishment of sister chromatid cohesion: the role of the clamp loaders. Parnas O, Kupiec M. Cell Cycle. 2010 Dec 1;9(23):4615. No abstract available.  PMID:20571511 | PMCID:PMC2928695
     

  • Reconstructing ancestral genomic sequences by co-evolution: formal definitions, computational issues, and biological examples. Tuller T, Birin H, Kupiec M, Ruppin E. J Comput Biol. 2010 Sep;17(9):1327-44. doi: 10.1089/cmb.2010.0112. PMID:20174551 | PMCID:PMC2824753
     

  • Elg1, an alternative subunit of the RFC clamp loader, preferentially interacts with SUMOylated PCNA. Parnas O, Zipin-Roitman A, Pfander B, Liefshitz B, Mazor Y, Ben-Aroya S, Jentsch S, Kupiec M. EMBO J. 2010 Aug 4;29(15):2611-22. doi: 10.1038/emboj.2010.128. Epub 2010 Jun 22. PMID:20160707 | PMCID:PMC2835564
     

  • Proteasome nuclear activity affects chromosome stability by controlling the turnover of Mms22, a protein important for DNA repair. Ben-Aroya S, Agmon N, Yuen K, Kwok T, McManus K, Kupiec M, Hieter P. PLoS Genet. 2010 Feb 19;6(2):e1000852. doi: 10.1371/journal.pgen.1000852. PMID:20133581 | PMCID:PMC2840511
     

  • Different sets of QTLs influence fitness variation in yeast. Romano GH, Gurvich Y, Lavi O, Ulitsky I, Shamir R, Kupiec M. Mol Syst Biol. 2010;6:346. doi: 10.1038/msb.2010.1. Epub 2010 Feb 16. PMID:20096103 | PMCID:PMC3224649
     

  • Translation efficiency is determined by both codon bias and folding energy. Tuller T, Waldman YY, Kupiec M, Ruppin E. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3645-50. doi: 10.1073/pnas.0909910107. Epub 2010 Feb 2. PMID:20066030 | PMCID:PMC2794365
     

  • Discovering local patterns of co-evolution: computational aspects and biological examples. Tuller T, Felder Y, Kupiec M. BMC Bioinformatics. 2010 Jan 22;11:43. doi: 10.1186/1471-2105-11-43. PMID:19948819 | PMCID:PMC2798824
     

  • Understanding gene sequence variation in the context of transcription regulation in yeast. Gat-Viks I, Meller R, Kupiec M, Shamir R. PLoS Genet. 2010 Jan;6(1):e1000800. doi: 10.1371/journal.pgen.1000800. Epub 2010 Jan 8. PMID:19698117 | PMCID:PMC2737003
     

  • Reconstructing ancestral gene content by coevolution. Tuller T, Birin H, Gophna U, Kupiec M, Ruppin E. Genome Res. 2010 Jan;20(1):122-32. doi: 10.1101/gr.096115.109. Epub 2009 Nov 30. PMID:19553188 | PMCID:PMC2731894
     

  • Properties of untranslated regions of the S. cerevisiae genome. Tuller T, Ruppin E, Kupiec M. BMC Genomics. 2009 Aug 22;10:391. doi: 10.1186/1471-2164-10-391. PMID:19546237 | PMCID:PMC2725747
     

  • Analysis of repair mechanism choice during homologous recombination. Agmon N, Pur S, Liefshitz B, Kupiec M. Nucleic Acids Res. 2009 Aug;37(15):5081-92. doi: 10.1093/nar/gkp495. Epub 2009 Jun 23. PMID:19536156
     

  • TOR complex 2 controls gene silencing, telomere length maintenance, and survival under DNA-damaging conditions. Schonbrun M, Laor D, Lֳ³pez-Maury L, Bֳ₪hler J, Kupiec M, Weisman R. Mol Cell Biol. 2009 Aug;29(16):4584-94. doi: 10.1128/MCB.01879-08. Epub 2009 Jun 22. PMID:19520767 | PMCID:PMC2724302
     

  • Adaptive prediction of environmental changes by microorganisms. Mitchell A, Romano GH, Groisman B, Yona A, Dekel E, Kupiec M, Dahan O, Pilpel Y. Nature. 2009 Jul 9;460(7252):220-4. doi: 10.1038/nature08112. Epub 2009 Jun 17. PMID:19465379 | PMCID:PMC2709590
     

  • Developmentally regulated MAPK pathways modulate heterochromatin in Saccharomyces cerevisiae. Mazor Y, Kupiec M. Nucleic Acids Res. 2009 Aug;37(14):4839-49. doi: 10.1093/nar/gkp512. Epub 2009 Jun 11. PMID:19430531 | PMCID:PMC2676507
     

  • A complex-centric view of protein network evolution. Yosef N, Kupiec M, Ruppin E, Sharan R. Nucleic Acids Res. 2009 Jul;37(12):e88. doi: 10.1093/nar/gkp414. Epub 2009 May 22. PMID:19416514 | PMCID:PMC2718514
     

  • The ELG1 clamp loader plays a role in sister chromatid cohesion. Parnas O, Zipin-Roitman A, Mazor Y, Liefshitz B, Ben-Aroya S, Kupiec M. PLoS One. 2009;4(5):e5497. doi: 10.1371/journal.pone.0005497. Epub 2009 May 11. PMID:19386622 | PMCID:PMC2709559
     

  • Co-evolutionary networks of genes and cellular processes across fungal species. Tuller T, Kupiec M, Ruppin E. Genome Biol. 2009;10(5):R48. doi: 10.1186/gb-2009-10-5-r48. Epub 2009 May 5. PMID:19293828 | PMCID:PMC2671920
     

  • A genome-wide screen for essential yeast genes that affect telomere length maintenance. Ungar L, Yosef N, Sela Y, Sharan R, Ruppin E, Kupiec M. Nucleic Acids Res. 2009 Jul;37(12):3840-9. doi: 10.1093/nar/gkp259. Epub 2009 Apr 22. PMID:19270715 | PMCID:PMC2672901
     

  • Toward accurate reconstruction of functional protein networks. Yosef N, Ungar L, Zalckvar E, Kimchi A, Kupiec M, Ruppin E, Sharan R. Mol Syst Biol. 2009;5:248. doi: 10.1038/msb.2009.3. Epub 2009 Mar 17. PMID:19193148
     

  • Midzone organization restricts interpolar microtubule plus-end dynamics during spindle elongation. Fridman V, Gerson-Gurwitz A, Movshovich N, Kupiec M, Gheber L. EMBO Rep. 2009 Apr;10(4):387-93. doi: 10.1038/embor.2009.7. Epub 2009 Mar 6. PMID:18811952 | PMCID:PMC2592720
     

  • Higher-order genomic organization of cellular functions in yeast. Tuller T, Rubinstein U, Bar D, Gurevitch M, Ruppin E, Kupiec M. J Comput Biol. 2009 Feb;16(2):303-16. doi: 10.1089/cmb.2008.15TT. PMID:18787117 | PMCID:PMC2567166
     

  • Evolutionary rate and gene expression across different brain regions. Tuller T, Kupiec M, Ruppin E. Genome Biol. 2008;9(9):R142. doi: 10.1186/gb-2008-9-9-r142. PMID:18628749 | PMCID:PMC2516364
     

  • Large-scale reconstruction and phylogenetic analysis of metabolic environments. Borenstein E, Kupiec M, Feldman MW, Ruppin E. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14482-7. doi: 10.1073/pnas.0806162105. Epub 2008 Sep 11. PMID:18456860 | PMCID:PMC2446676
     

  • From E-MAPs to module maps: dissecting quantitative genetic interactions using physical interactions. Ulitsky I, Shlomi T, Kupiec M, Shamir R. Mol Syst Biol. 2008;4:209. doi: 10.1038/msb.2008.42. Epub 2008 Jul 15. PMID:18319724 | PMCID:PMC2290934
     

  • Functional characterization of CgCTR2, a putative vacuole copper transporter that is involved in germination and pathogenicity in Colletotrichum gloeosporioides. Barhoom S, Kupiec M, Zhao X, Xu JR, Sharon A. Eukaryot Cell. 2008 Jul;7(7):1098-108. doi: 10.1128/EC.00109-07. Epub 2008 May 2. PMID:18159940 | PMCID:PMC2230678
     

  • A systems-level approach to mapping the telomere length maintenance gene circuitry. Shachar R, Ungar L, Kupiec M, Ruppin E, Sharan R. Mol Syst Biol. 2008;4:172. doi: 10.1038/msb.2008.13. Epub 2008 Mar 4. PMID:18040271
     

  • Determinants of protein abundance and translation efficiency in S. cerevisiae. Tuller T, Kupiec M, Ruppin E. PLoS Comput Biol. 2007 Dec;3(12):e248. PMID:17670800 | PMCID:PMC1976456
     

  • Finding a match: how do homologous sequences get together for recombination? Barzel A, Kupiec M. Nat Rev Genet. 2008 Jan;9(1):27-37. Review. PMID:17389877 | PMCID:PMC1847952
     

  • Capture of linear fragments at a double-strand break in yeast. Haviv-Chesner A, Kobayashi Y, Gabriel A, Kupiec M. Nucleic Acids Res. 2007;35(15):5192-202. Epub 2007 Aug 1. PMID:17325681
     

  • Genetic interactions in yeast: is robustness going bust? Kupiec M, Sharan R, Ruppin E. Mol Syst Biol. 2007;3:97. Epub 2007 Mar 27. No abstract available.  PMID:17179073 | PMCID:PMC1840069
     

  • A genome-wide analysis in Saccharomyces cerevisiae demonstrates the influence of chromatin modifiers on transcription. Steinfeld I, Shamir R, Kupiec M. Nat Genet. 2007 Mar;39(3):303-9. PMID:17171376
     

  • Opposite effects of tor1 and tor2 on nitrogen starvation responses in fission yeast. Weisman R, Roitburg I, Schonbrun M, Harari R, Kupiec M. Genetics. 2007 Mar;175(3):1153-62. Epub 2006 Dec 18. PMID:16941010
     

  • A role for the yeast cell cycle/splicing factor Cdc40 in the G1/S transition. Kaplan Y, Kupiec M. Curr Genet. 2007 Feb;51(2):123-40. Epub 2006 Dec 14. PMID:16729037 | PMCID:PMC1681453
     

  • Multiple knockout analysis of genetic robustness in the yeast metabolic network. Deutscher D, Meilijson I, Kupiec M, Ruppin E. Nat Genet. 2006 Sep;38(9):993-8. PMID:16448026
     

  • Integrative analysis of genome-wide experiments in the context of a large high-throughput data compendium. Tanay A, Steinfeld I, Kupiec M, Shamir R. Mol Syst Biol. 2005;1:2005.0002. Epub 2005 Mar 29. PMID:16322764 | PMCID:PMC1289391
     

  • Multi-knockout genetic network analysis: the Rad6 example. Kaufman A, Kupiec M, Ruppin E. Proc IEEE Comput Syst Bioinform Conf. 2004:332-40. PMID:15960846 | PMCID:PMC1181813
     

  • Quantitative analysis of genetic and neuronal multi-perturbation experiments. Kaufman A, Keinan A, Meilijson I, Kupiec M, Ruppin E. PLoS Comput Biol. 2005 Nov;1(6):e64. Epub 2005 Nov 25. PMID:15725622
     

  • Evidence for abundant transcription of non-coding regions in the Saccharomyces cerevisiae genome. Havilio M, Levanon EY, Lerman G, Kupiec M, Eisenberg E. BMC Genomics. 2005 Jun 16;6:93. PMID:15655342
     

  • The Elg1 replication factor C-like complex: a novel guardian of genome stability. Aroya SB, Kupiec M. DNA Repair (Amst). 2005 Apr 4;4(4):409-17. Review. PMID:15551135
     

  • Cell cycle-dependent regulation of double-strand break repair: a role for the CDK. Aylon Y, Kupiec M. Cell Cycle. 2005 Feb;4(2):259-61. Epub 2005 Feb 7. 
     

  • The yeast VPS genes affect telomere length regulation. Rog O, Smolikov S, Krauskopf A, Kupiec M. Curr Genet. 2005 Jan;47(1):18-28. Epub 2004 Nov 18. PMID:15549137 | PMCID:PMC535085
     

  • The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle. Aylon Y, Liefshitz B, Kupiec M. EMBO J. 2004 Dec 8;23(24):4868-75. Epub 2004 Nov 18. PMID:15279765
     

  • Regulation of leucine uptake by tor1+ in Schizosaccharomyces pombe is sensitive to rapamycin. Weisman R, Roitburg I, Nahari T, Kupiec M. Genetics. 2005 Feb;169(2):539-50. Epub 2004 Sep 30. PMID:15260973
     

  • DSB repair: the yeast paradigm. Aylon Y, Kupiec M. DNA Repair (Amst). 2004 Aug-Sep;3(8-9):797-815. Review. PMID:15161972 | PMCID:PMC423251
     

  • The compact chromatin structure of a Ty repeated sequence suppresses recombination hotspot activity in Saccharomyces cerevisiae. Ben-Aroya S, Mieczkowski PA, Petes TD, Kupiec M. Mol Cell. 2004 Jul 23;15(2):221-31. PMID:15133121 | PMCID:PMC419462
     

  • A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Askree SH, Yehuda T, Smolikov S, Gurevich R, Hawk J, Coker C, Krauskopf A, Kupiec M, McEachern MJ. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8658-63. Epub 2004 May 25. PMID:15090068 | PMCID:PMC406509
     

  • The Saccharomyces cerevisiae gene CDC40/PRP17 controls cell cycle progression through splicing of the ANC1 gene. Dahan O, Kupiec M. Nucleic Acids Res. 2004 May 7;32(8):2529-40. Print 2004. PMID:15082239
     

  • Site-specific genomic (SSG) and random domain-localized (RDL) mutagenesis in yeast. Gray M, Kupiec M, Honigberg SM. BMC Biotechnol. 2004 Apr 16;4:7. PMID:14973197 | PMCID:PMC365731
     

  • New insights into the mechanism of homologous recombination in yeast. Aylon Y, Kupiec M. Mutat Res. 2004 May;566(3):231-48. Review. PMID:12944484 | PMCID:PMC193701
     

  • Revealing modularity and organization in the yeast molecular network by integrated analysis of highly heterogeneous genomewide data. Tanay A, Sharan R, Kupiec M, Shamir R. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2981-6. Epub 2004 Feb 18. PMID:12909721 | PMCID:PMC187881
     

  • The checkpoint protein Rad24 of Saccharomyces cerevisiae is involved in processing double-strand break ends and in recombination partner choice. Aylon Y, Kupiec M. Mol Cell Biol. 2003 Sep;23(18):6585-96. PMID:12684846
     

  • ELG1, a yeast gene required for genome stability, forms a complex related to replication factor C. Ben-Aroya S, Koren A, Liefshitz B, Steinlauf R, Kupiec M. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9906-11. Epub 2003 Aug 8. PMID:12589024 | PMCID:PMC151415
     

  • Pitfalls of the synthetic lethality screen in Saccharomyces cerevisiae: an improved design. Koren A, Ben-Aroya S, Steinlauf R, Kupiec M. Curr Genet. 2003 Apr;43(1):62-9. Epub 2003 Feb 5. PMID:12556499 | PMCID:PMC141147
     

  • A Saccharomyces cerevisiae mutant with increased virulence. Wheeler RT, Kupiec M, Magnelli P, Abeijon C, Fink GR. Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2766-70. Epub 2003 Feb 14. PMID:12491006
     

  • Molecular dissection of mitotic recombination in the yeast Saccharomyces cerevisiae. Aylon Y, Liefshitz B, Bitan-Banin G, Kupiec M. Mol Cell Biol. 2003 Feb;23(4):1403-17. PMID:12384582 | PMCID:PMC137127
     

  • Control of meiotic recombination initiation: a role for the environment? Koren A, Ben-Aroya S, Kupiec M. Curr Genet. 2002 Dec;42(3):129-39. Epub 2002 Oct 30. Review. PMID:11522493
     

  • Mutations in genes of Saccharomyces cerevisiae encoding pre-mRNA splicing factors cause cell cycle arrest through activation of the spindle checkpoint. Dahan O, Kupiec M. Nucleic Acids Res. 2002 Oct 15;30(20):4361-70. PMID:11425518

​​

  • Deletion of the SRS2 gene suppresses elevated recombination and DNA damage sensitivity in rad5 and rad18 mutants of Saccharomyces cerevisiae. Friedl AA, Liefshitz B, Steinlauf R, Kupiec M. Mutat Res. 2001 Jul 12;486(2):137-46. PMID:11102353 | PMCID:PMC1461362
     

  • Functional analyses of interacting factors involved in both pre-mRNA splicing and cell cycle progression in Saccharomyces cerevisiae. Russell CS, Ben-Yehuda S, Dix I, Kupiec M, Beggs JD. RNA. 2000 Nov;6(11):1565-72. PMID:10953878
     

  • Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae. Ben-Yehuda S, Dix I, Russell CS, McGarvey M, Beggs JD, Kupiec M. Genetics. 2000 Dec;156(4):1503-17. PMID:10924495
     

  • Recombination between divergent sequences leads to cell death in a mismatch-repair-independent manner. Inbar O, Kupiec M. Curr Genet. 2000 Jul;38(1):23-32. PMID:10915867
     

  • The relationship between homology length and crossing over during the repair of a broken chromosome. Inbar O, Liefshitz B, Bitan G, Kupiec M. J Biol Chem. 2000 Oct 6;275(40):30833-8. PMID:10628969 | PMCID:PMC1460917
     

  • Damage-induced recombination in the yeast Saccharomyces cerevisiae. Kupiec M. Mutat Res. 2000 Jun 30;451(1-2):91-105. Review. PMID:10447590
     

  • Extensive genetic interactions between PRP8 and PRP17/CDC40, two yeast genes involved in pre-mRNA splicing and cell cycle progression. Ben-Yehuda S, Russell CS, Dix I, Beggs JD, Kupiec M. Genetics. 2000 Jan;154(1):61-71. PMID:10333746
     

  • Characterization of the role played by the RAD59 gene of Saccharomyces cerevisiae in ectopic recombination. Jablonovich Z, Liefshitz B, Steinlauf R, Kupiec M. Curr Genet. 1999 Aug;36(1-2):13-20. PMID:10330153 | PMCID:PMC104372

​​

  • Homology search and choice of homologous partner during mitotic recombination. Inbar O, Kupiec M. Mol Cell Biol. 1999 Jun;19(6):4134-42. PMID:10094305 | PMCID:PMC1369765
     

  • Functional conservation between the argininosuccinate lyase of the archaeon Methanococcus maripaludis and the corresponding bacterial and eukaryal genes. Cohen-Kupiec R, Kupiec M, Sandbeck K, Leigh JA. FEMS Microbiol Lett. 1999 Apr 1;173(1):231-8. PMID:9862477
     

  • The identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae. Dix I, Russell C, Yehuda SB, Kupiec M, Beggs JD. RNA. 1999 Mar;5(3):360-8. PMID:9769104 | PMCID:PMC1369702
     

  • Efficient initiation of S-phase in yeast requires Cdc40p, a protein involved in pre-mRNA splicing. Boger-Nadjar E, Vaisman N, Ben-Yehuda S, Kassir Y, Kupiec M. Mol Gen Genet. 1998 Nov;260(2-3):232-41. PMID:9637242
     

  • Identification and functional analysis of hPRP17, the human homologue of the PRP17/CDC40 yeast gene involved in splicing and cell cycle control. Ben Yehuda S, Dix I, Russell CS, Levy S, Beggs JD, Kupiec M. RNA. 1998 Oct;4(10):1304-12. PMID:9309168
     

  • Genetic interactions between mutants of the 'error-prone' repair group of Saccharomyces cerevisiae and their effect on recombination and mutagenesis. Liefshitz B, Steinlauf R, Friedl A, Eckardt-Schupp F, Kupiec M. Mutat Res. 1998 Mar;407(2):135-45. PMID:9201271
     

  • cDNA-mediated Ty recombination can take place in the absence of plus-strand cDNA synthesis, but not in the absence of the integrase protein. Nevo-Caspi Y, Kupiec M. Curr Genet. 1997 Jul;32(1):32-40. PMID:8913740 | PMCID:PMC1207634
     

  • Damage-induced ectopic recombination in the yeast Saccharomyces cerevisiae. Kupiec M, Steinlauf R. Mutat Res. 1997 Jun 9;384(1):33-44. PMID:7498763 | PMCID:PMC1206687
     

  • Induction of Ty recombination in yeast by cDNA and transcription: role of the RAD1 and RAD52 genes. Nevo-Caspi Y, Kupiec M. Genetics. 1996 Nov;144(3):947-55. PMID:7635309 | PMCID:PMC1206572
     

  • The role of DNA repair genes in recombination between repeated sequences in yeast. Liefshitz B, Parket A, Maya R, Kupiec M. Genetics. 1995 Aug;140(4):1199-211. PMID:7753021
     

  • Recombination of Ty elements in yeast can be induced by a double-strand break. Parket A, Inbar O, Kupiec M. Genetics. 1995 May;140(1):67-77. PMID:7809107 | PMCID:PMC45509
     

  • The role of Saccharomyces cerevisiae Cdc40p in DNA replication and mitotic spindle formation and/or maintenance. Vaisman N, Tsouladze A, Robzyk K, Ben-Yehuda S, Kupiec M, Kassir Y. Mol Gen Genet. 1995 Apr 20;247(2):123-36. PMID:8056321 | PMCID:PMC1205951
     

  • Transcriptional induction of Ty recombination in yeast. Nevo-Caspi Y, Kupiec M. Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12711-5. PMID:8319297
     

  • Plasmid-mediated induction of recombination in yeast. Silberman R, Kupiec M. Genetics. 1994 May;137(1):41-8. PMID:8455564
     

  • Donation of information to the unbroken chromosome in double-strand break repair. Roitgrund C, Steinlauf R, Kupiec M. Curr Genet. 1993 May-Jun;23(5-6):414-22. PMID:1435735
     

  • Donation: a new, facile method of gene replacement in yeast. Roitgrund C, Steinlauf R, Kupiec M. Mol Gen Genet. 1993 Feb;237(1-2):306-10. PMID:1328855 | PMCID:PMC360368
     

  • Effect of donor copy number on the rate of gene conversion in the yeast Saccharomyces cerevisiae. Melamed C, Kupiec M. Mol Gen Genet. 1992 Oct;235(1):97-103. PMID:1372387 | PMCID:PMC369604
     

  • Ectopic recombination between Ty elements in Saccharomyces cerevisiae is not induced by DNA damage. Parket A, Kupiec M. Mol Cell Biol. 1992 Oct;12(10):4441-8. PMID:2698829
     

  • Involvement of cDNA in homologous recombination between Ty elements in Saccharomyces cerevisiae. Melamed C, Nevo Y, Kupiec M. Mol Cell Biol. 1992 Apr;12(4):1613-20. PMID:2841590 | PMCID:PMC363514
     

  • Recombination in yeast and the recombinant DNA technology. Petes TD, Detloff P, Jinks-Robertson S, Judd SR, Kupiec M, Nag D, Stapleton A, Symington LS, Vincent A, White M. Genome. 1989;31(2):536-40. Review. PMID:2841187 | PMCID:PMC1203441
     

  • Meiotic recombination between repeated transposable elements in Saccharomyces cerevisiae. Kupiec M, Petes TD. Mol Cell Biol. 1988 Jul;8(7):2942-54. PMID:3523226
     

  • Allelic and ectopic recombination between Ty elements in yeast. Kupiec M, Petes TD. Genetics. 1988 Jul;119(3):549-59. PMID:3528754
     

  • DNA-repair characterization of cdc40-1, a cell-cycle mutant of Saccharomyces cerevisiae. Kupiec M, Simchen G. Mutat Res. 1986 Aug;162(1):33-40. 
     

  • Regulation of the RAD6 gene of Saccharomyces cerevisiae in the mitotic cell cycle and in meiosis. Kupiec M, Simchen G. Mol Gen Genet. 1986 Jun;203(3):538-43. PMID:3327607
     

  • The RAD50 gene of Saccharomyces cerevisiae is not essential for vegetative growth. Kupiec M. Curr Genet. 1986;10(6):487-9. PMID:24177994
     

  • Cloning and mapping of CDC40, a Saccharomyces cerevisiae gene with a role in DNA repair. Kassir Y, Kupiec M, Shalom A, Simchen G. Curr Genet. 1985;9(4):253-7. PMID:6323924
     

  • Cloning and integrative deletion of the RAD6 gene of Saccharomyces cerevisiae. Kupiec M, Simchen G. Curr Genet. 1984 Oct;8(8):559-66. doi: 10.1007/BF00395700. 
     

  • Cloning and mapping of the RAD50 gene of Saccharomyces cerevisiae. Kupiec M, Simchen G. Mol Gen Genet. 1984;193(3):525-31. 

bottom of page